CONTINUOUS HEMILAMINECTOMY OF NINE VERTEBRAE CAN BE PERFORMED SAFELY IN LARGE BREED DOGS: A CASE REPORT OF A GERMAN SHEPHERD DOG WITH INTERVERTEBRAL DISC EXTRUSION AND EXTENSIVE EXTRADURAL HEMORRHAGE

Continuous hemilaminectomy of nine vertebrae can be performed safely in large breed dogs: a case report of a German Shepherd Dog with intervertebral disc extrusion and extensive extradural hemorrhage

Background: Extended, continuous hemilaminectomy has only been reported in small to medium-sized dogs so far.It remains unclear whether excessive continuous hemilaminectomy can also be performed safely in large breed dogs.Case Description: We describe the surgical treatment and clinical outcome of a 5-year-old German Shepherd Dog that was presented

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CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX

Poxvirus vectors represent versatile modalities for engineering novel vaccines and cancer immunotherapies.In addition to their oncolytic capacity and immunogenic influence, they can be readily engineered to express multiple large transgenes.However, the integration of multiple payloads into Front Load Washer poxvirus genomes by traditional recombin

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